Tagged: asco

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#195: Warfarin, from Cow Disease to Medicine

Warfarin is one of the most successful drugs of all time. Seventy years after it was first synthesized, warfarin is still the most widely prescribed anticoagulant. Warfarin has a unique story. What began as depression-era research into a mysterious disease of cattle ended up producing two life-saving medicines and a rat poison that are still in use today.

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#194: Spathulariopsis velutipes

Spathulariopsis velutipes is an odd little mushroom that looks like a spatula or a canoe paddle, though perhaps in a half-melted kind of way. Its common names include “velvety fairy fan,” “velvet foot Spathularia,” and variations on those. This ascomycete is an earth tongue look-alike (ETLA)* that is easily differentiated from similar mushrooms thanks to its unique shape and the strikingly different colors and textures of its head and stipe. I always enjoy finding this mushroom because of its unique appearance.

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2017 Summer News Update

Fungi appear in the news with surprising frequency. However, many of those stories do not provide any new information. Below is a summary of what we’ve learned about fungi from May through early July 2017. Read below to learn about: early fungal fossils, fungal epigenetics, the best way to cook mushrooms, liver disease, malaria, and more! Visit the associated links to get the full story.

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#188: Leotia lubrica, Jelly Babies

For some reason, the strange little mushrooms produced by the ascomycete Leotia lubrica are called “Jelly Babies” (or “Jellybabies”). They do look a little like the mushroom version of gummy fruit snacks, but that’s as close as I can get to understanding their common name. When fresh, these small yellow and brown mushrooms have a smooth but wrinkled and slimy cap held aloft by a gently curving stalk, so they do look somewhat like a gelatinous morsel on a stick.

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2017 Spring News Update

Fungi appear in the news with surprising frequency. However, many of those stories do not provide any new information. Below is a summary of what we’ve learned about fungi from March through April 2017. Read below to learn about: C. auris in the U.S., aflatoxin-destroying corn, viruses defying fungal incompatibility, fungus-farming ant evolution, bat and salamander diseases, and more! Visit the associated links to get the full story.

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#171: Reindeer Lichen

Reindeer Lichens grow in northern temperate forests, boreal forests, and even in the tundra. They are highly branched, fruticose lichens that are a primary food source for reindeer (also called caribou in North America). These lichens are sometimes called “Reindeer Moss,” even though they are lichens and not moss.

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2016 Fall News Update

Fungi appear in the news with surprising frequency. However, many of those stories do not provide any new information. Below is a summary of what we’ve learned about fungi from November 2016 Through February 2017. Read below to learn about: two-fungi lichens, the fate of bananas, battery recycyling, Crohn’s disease, orcas, human pathogenic fungi, and more! Visit the associated links to get the full story.

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#166: Chlorociboria spp., Green Stain Fungi

Chlorociboria spp. include some of my favorite fungi. Although you don’t see their mushrooms very often, it is quite common to find pieces of wood that have been stained blue-green by Chlorociboria mycelium. This attractive and unusual coloration earned these fungi many common names, including “Green Stain Fungus,” “Blue Stain Fungus,” “Turquoise Elfcup,” and various combinations and derivatives of those. I enjoy finding the stained wood, especially during dry periods or over the winter, when mushrooms are scarce.

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#164: Histoplasmosis

Histoplasmosis is a fungal disease caused by the fungus Histoplasma capsulatum. Like the other true human fungal pathogens, H. capsulatum lives as a mold in the environment but switches to an infective yeast form in the body. In nature, H. capsulatum grows on bird or bat droppings. This fungus is very common, especially in the Ohio and Mississippi River valley areas. However, H. capsulatum very rarely causes disease. As with most fungal diseases, people with a weakened immune system are most at risk of acquiring histoplasmosis.

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#163: Valley Fever, Coccidioidomycosis

Coccidioidomycosis, otherwise known as “Valley fever,” is the most virulent human fungal pathogen. The disease is caused by the fungi Coccidioides immitis and C. posadasii, which normally live in arid soils. When they are disturbed by wind, construction, or human activity, spores from these fungi can become airborne and end up in peoples’ lungs. There, the spores germinate and can cause infection. Most of the time, the infection is mild and does not need to be treated. Occasionally, however, this progresses to more severe forms that sometimes require lifelong treatment. As with other human fungal diseases, Valley fever is more likely to cause severe disease in people with weakened immune systems.